Tulane Outbreak – June 7, 2022

Featured COVID Headlines

Omicron BA.4 and BA.5: Starting From Scratch Yet Again – MedPageToday

Coronaviruses are single-stranded RNA viruses with large genomes and, until recently, consisted of the mild 229E, OC43, L69, and H53U1 strains, and the “novel” SARS and MERS strains. Sometime in late 2019, a third “novel” coronavirus called the “Wuhan” strain emerged. This began what we now know as the COVID-19 pandemic. With subsequent mutation, “variants of concern” soon emerged, starting with Alpha, and the most significant subsequently being Delta and then Omicron.

New variants are poised to keep Covid-19 circulating at high levels throughout the summer – CNN

Even as the US grapples with its most recent wave of Covid-19, new research suggests that variants on the horizon may keep case levels high. The next influx of infections will probably come from the newer Omicron subvariants BA.4 and BA.5, two closely related viruses that were first characterized in South Africa and that landed in the United States around late March, according to the gene sequence sharing site GISAID.

Why boosted Americans seem to be getting more COVID-19 infections – CBS News Video

My family got COVID. So why did we test negative? – Seattle Times

As a science journalist, I’ve read dozens of research papers about COVID-19, and I’ve interviewed so many virologists, infectious disease physicians and immunologists over the past two years that I’ve lost count. But nothing prepared me for what happened after my 7-year-old daughter tested positive for COVID-19 nearly two weeks ago.

Coronavirus FAQ: I got COVID. Then I got it again. What’s the deal with reinfection? – NPR

ou got sick with COVID back in January, so you figured you were done with the virus for a while. But then you began feeling a scratchy throat and a runny nose, took a home test just in case — and that second line blazed red once again.

How long covid could change the way we think about disability – Washington Post

Mallory Stanislawczyk was hesitant to make the call. She hadn’t spoken to her friend in years. But the friend, who gets around in a wheelchair, was the only person the 34-year-old nurse practitioner could think of who would understand her questions. About being ready to accept help. About using a wheelchair. And about the new identity her battle with long covid had thrust on her.

COVID-19 deaths have outpaced deaths from pneumonia and flu – MedNewsToday

The Office for National Statistics (ONS) in the United Kingdom released a report comparing deaths from COVID-19 to deaths from pneumonia and flu.
They found that since the COVID-19 outbreak, COVID-19 deaths have outpaced deaths from pneumonia and flu.
Experts say that these results highlight the need to continue following public safety measures such as getting vaccinated and wearing masks.

Using AI to Advance Understanding of Long COVID Syndrome – NIH Director’s Blog

The COVID-19 pandemic continues to present considerable public health challenges in the United States and around the globe. One of the most puzzling is why many people who get over an initial and often relatively mild COVID illness later develop new and potentially debilitating symptoms. These symptoms run the gamut including fatigue, shortness of breath, brain fog, anxiety, and gastrointestinal trouble.

There’s a Reason Kim Jong-un Wants Us to Know About North Korea’s Covid Outbreak – NYT

For more than two years, isolated North Korea claimed success in keeping out Covid and even rebuffed multiple offers of vaccines, calling them unnecessary. Last month, that changed. In a series of urgent dispatches, North Korea’s state media announced that an unspecified fever was spreading “explosively.” The nation went into lockdown. More than four million cases have been reported, with dozens of deaths.

How to Compare COVID Deaths for Vaccinated and Unvaccinated People – Scientific American

The death rate among unvaccinated people is still far higher than that among the vaccinated even though vaccinated people now make up a significant proportion of deaths

Emerging Infectious Disease Headlines

Pediatric Hepatitis

Hepatitis: What could be causing the mysterious outbreak in children?

As of 26 May, the World Health Organization had received 650 reports of probable, sudden-onset hepatitis with no known cause in children across 33 countries

Monkeypox

Monkeypox cases soar in UK, with more than 300 confirmed – CIDRAP

Today, the UK Health Security Agency (UKHSA) said an additional 77 monkeypox cases have been confirmed across the United Kingdom, bringing the outbreak total to 302 as of yesterday. There are currently 287 confirmed cases in England, 10 in Scotland, 2 in Northern Ireland, and 3 in Wales.

‘Testing bottleneck’ for monkeypox puts hope of containment at risk, experts warn – STAT

Infectious disease specialists are growing increasingly concerned by the U.S. strategy for testing for monkeypox, warning that it’s creating a bottleneck and squandering the limited time the country may have to get the outbreak under control.

Monkeypox cases are going undetected or misdiagnosed – NPR

The monkeypox outbreak has grown to more than 800 cases in dozens of countries. Officials say cases are going undetected because the disease looks different than what’s described in medical textbooks.

Ring vaccination might help curtail monkeypox outbreaks – Harvard Health

By now, you’ve probably heard that there is a monkeypox outbreak traveling around the globe. Cases have spread far and wide, including in the US, Canada, Europe, and Australia. It’s the largest outbreak ever recorded outside of western and central Africa, where monkeypox is common.

Vaccine Headlines

Don’t Wait to Get Your Kid Vaccinated – The Atlantic

Karen Ocwieja delivered her twin sons last June, just weeks before Delta broke across the American Northeast. For months, she and her husband sheltered the boys, who’d been born premature, limiting their exposures to friends, family, and other kids, hoping to guard them from COVID’s worst. But all four of them still ended up catching the virus this January—the boys’ first bona fide illness. Then, in May, the twins tested positive again. Born with Ocwieja’s antibodies from pregnancy and now churning out their own, they likely will never know a world without COVID.

The U.S. has wasted over 82 million Covid vaccine doses – NBC News

Vaccine providers say declining demand, large minimum orders and multidose vials make it hard to avoid waste while still offering shots to anyone who wants them.

U.S. has more than 36,000 Jynneos monkeypox vaccine doses immediately available in national stockpile – NBC News

The U.S. has more than 36,000 doses of the Jynneos vaccine immediately available in the strategic national stockpile. The federal government has asked the manufacturer, Bavarian Nordic, to send another 36,000 doses in the near future. Bavarian Nordic also holds 1 million U.S.-owned doses and can fill another 16.4 million shots upon request by the federal government. Jynneos is the only vaccine FDA approved to treat monkeypox. The older smallpox vaccine ACAM2000 can also be used against monkeypox. The U.S. has more than 100 million doses of ACAM2000.

U.S. FDA flags risk of heart inflammation after Novavax COVID vaccine – Reuters

The U.S. Food and Drug Administration hasraised concerns about a possible risk of heart inflammation from Novavax Inc’s (NVAX.O)COVID-19 vaccine, even as the company’s data showed it could reduce the chances of mild-to-severe disease.

Clinical Considerations

COVID survivors struggle with pulmonary embolisms, breathing issues – CIDRAP

A large study of adults in the United States who survived COVID-19 during the first 2 years of the pandemic found that they had twice the risk of developing pulmonary embolism or respiratory conditions in the year following infection.

Pfizer’s Paxlovid reduces COVID risk in seniors regardless of vaccine status -study – Reuters

Pfizer Inc’s (PFE.N) antiviral treatment Paxlovid reduces COVID-19 hospitalization and death rates in vaccinated and unvaccinated patients 65 years and older, according to a new study in Israel conducted during the rise of the Omicron variant of the coronavirus.

Official Reporting for June 7, 2022

World Health Organization

Weekly Epi Update June 1, 2022(latest release)

New Cases: 204,539 ⬇︎

Confirmed Cases: 84,965,849

Deaths: 6,293,414

Johns Hopkins

Confirmed Cases: 532,742,007
Deaths: 1,009,076

Centers for Disease Control and Prevention (CDC)

Total cases: 84,636,391 (+98,513 New Cases) ⬇︎
Total deaths: 1,003,925 (+247 New Deaths) ⬆︎

Science and Tech

None Today

Psychological and Sociological Impact

None Today

Published Research

Long COVID after breakthrough SARS-CoV-2 infection – Nature

Post–COVID Conditions Among Adult COVID-19 Survivors Aged 18–64 and ≥65 Years — United States, March 2020–November 2021 – CDC

Misinformation, Disinformation, and Conspiracy Theories

Stephanie’s Story: How COVID Misinformation Affected One Family – NPR

Stephanie was usually careful about her health and regular vaccinations. But then she got into sharing conspiracy-filled videos and fringe ideas. When COVID hit, misinformation put her and her husband at risk. Science correspondent and editor Geoff Brumfiel shares with Emily Kwong what he learned in reporting Stephanie’s story.

Coping with COVID