Tulane Outbreak Daily | March 20, 2020

Featured Headlines

Disease Doubling Faster Now; Deaths Top 10,000: Virus Update – Bloomberg

The World Health Organization said the disease is now infecting people at a faster pace. It took three months for the first 100,000 cases, but only 12 days for the next 100,000.

‘It’s Not the Exact Same Virus Everywhere in the World’ – MedPage Today

Preprint manuscript suggests COVID-19 virus has already mutated into multiple strains. [Link to PrePub paper]

WHO Adopts Test Method That Helped Stifle Ebola for Coronavirus – Bloomberg

In the Solidarity trials, researchers will test four therapies, some of which are already used in people, to treat Covid-19: Gilead Sciences Inc.’s experimental remdesivir, AbbVie Inc.’s Kaletra (used to treat HIV infection), Kaletra with an anti-inflammatory treatment called interferon-beta, and the malaria drug chloroquine.

The US Coronavirus Death Rate Is Falling, and Germany’s More So – American Institute of Economic Research

China, Where COVID-19 Was First Detected, Reports No New Local Cases Of Coronavirus – Forbes

China reported no new locally transmitted cases of coronavirus—but marked a spike in new cases from overseas—prompting authorities there to enforce strict new quarantine measures on travelers from abroad.

SARS-CoV-2 turned positive in a discharged patient with COVID-19 arouses concern regarding the present standard for dischargeIntl Journal of Infectious Diseases

How to manage these patients normatively is still challenging. We hereby reported an asymptomatic discharged patient with COVID-19 who was retested positive for SARS-CoV-2, which arouses concern regarding the present discharge standard of COVID-19.

U.K. asks Rolls-Royce and Jaguar to make ventilators in wartime-like effort – Washington Post

British government issued a cry for help from manufacturers — the builders of automobiles, jet engines, dialysis machines, excavation equipment — to switch their assembly lines over to make mechanical ventilators.

[Opinion] The Epic Failure of Coronavirus Testing in America – New York Times

The WHO has emphasized social distancing, find and isolate every person infected with Covid-19 — including those with mild cases of the disease who don’t turn up in doctor’s offices or hospitals.The U.S. has been conveying a very different message; If you suspect you’re infected, stay home. Even those who live in close quarters with someone who faces a higher risk of becoming severely ill or dying from the infection, have been discouraged from seeking testing unless they are having difficulty breathing.



Editor’s note: Regarding the case counts below, please consider due to limited testing capabilities in some locations, the real number of cases could be considerably higher.

Official Reporting


Total (new) cases in last 24 hours

Globally: 209,839 confirmed (16,556) 8,778 deaths (828)
Western Pacific Region: 92,333 confirmed (488) 3,377 deaths (20)
European Region: 87,108 confirmed (10,221) 4,084 deaths (591)
South-East Asia Region: 657 confirmed (119) 23 deaths (14)
Eastern Mediterranean Region: 19,518 confirmed (1,430) 1,161 deaths (150)
Region of the Americas: 9,144 confirmed (4,166) 119 deaths (50)
African Region: 367 confirmed (132) 7 deaths (3)

As of March 19, 2020

Confirmed Cases: 213,254
Deaths: 8,843
Cases < 15 Days 120,187

Total cases: 10,442
Total deaths: 150
Jurisdictions reporting cases: 54 (50 states, District of Columbia, Puerto Rico, Guam, and US Virgin Islands)

Travel Related: 290
Close Contact: 310
Under Investigation: 9,842
Total Cases: 10,442

Surveillance Headlines


California: Gov Issues ‘Stay At Home’ Order As Coronavirus Infections Rise – NPR

Gov. Gavin Newsom has ordered California’s 40 million residents to stay at home indefinitely.

New York: Has Over 40 Percent of U.S. Coronavirus Cases – New York Times

“We now constitute 30 percent of the coronavirus cases in the United States of America, 70 percent of the cases in the state of New York,” Mr. de Blasio said on MSNBC. “We have to take really intense, radical action right away.


France: Officials expect to extend the country’s 2-week lockdown. There are 4,461 patients hospitalized, 1,122 of them in intensive care, 108 more deaths were reported, raising the fatality count to 372. CIDRAP

Germany: Confirmed cases passed the 10,000 mark, with the addition of 2,801 more cases today The country has now reported 10,999 cases, 20 of them fatal. CIDRAP

Germany/Bavaria: National shutdown looms in Germany as Bavaria imposes total lockdown – Yahoo Finance

Spain: The health minister today reported 3,431 new cases, pushing its total to 17,147, and 169 more deaths, lifting the fatality count to 767. The outbreak has overwhelmed Spain’s health system, and the health ministry announced a plan to enlist 50,000 retired health professionals and medical and nursing students to help. CIDRAP

Russia: Russia reported its first death, which involves a 79-year-old woman from Moscow who had underlying health conditions. Russia’s total cases are reported as 147. CIDRAP

South/Central America

WHO’s Pan American Health Organization (PAHO):  As of Mar 17, 37 countries in the region had reported 5,944 cases and 19 deaths. The United States accounts for the majority of the cases. CIDRAP

Nicaragua: Reported its first known case, in a man who had visited Panama CIDRAP

El Salvador: Announced its first, a citizen who had recently visited Italy. CIDRAP

Peru: Peru has 31 doctors under SARS-CoV-2 suspicion – Prensa Latina

Middle East

Iran: reported 1,046 new cases, lifting its total to 18,407, and 149 additional deaths, raising its fatality count to 1,284. CIDRAP

Qatar: reports 452 cases CIDRAP

Pakistan: reports 302 cases CIDRAP

Bahrain: reports 269 cases CIDRAP


Djibouti: The first case reported according to WHO EMRO. The patient is a traveler from Spain who arrived on a military flight; other passengers on the same flight will be quarantined. CIDRAP

Gambia, Mauritius, and Zambia have detected their first cases, raising the region’s total to 633 illnesses from 33 countries, 17 of them fatal. The three countries with the most cases include Egypt (210), South Africa (150), and Algeria (82). CIDRAP

Travel Advisories

Look up current travel advisories at US Department of State

U.S. CDC Travel Advisories

Infection Prevention

EPA Releases List of Anti-SARS-CoV-2 Surface Disinfectants – EPA

Unmasked: Experts explain necessary respiratory protection for COVID-19 – CIDRAP

How to operate building services to prevent the spread of COVID-19 virus SARS-CoV-2 – Estonian Research Council

Practical recommendations which cover ventilation system operation times, use of window airing, safe use of heat recovery sections, no use of recirculation in central ventilation systems as well as on the room level, and some explanation how to avoid overreactions which are easy to happen in situations with limited knowledge.

Science and Tech

Coronavirus drugs: Can antibodies from survivors help? – DW

Aside from a Covid-19 vaccine, antibodies from recovered patients could provide a short-term “passive immunization” to the disease. A German immunologist saved thousands of lives with the method 100 years ago.

Near Real-Time Studies Look for Behavioral Measures Vital to Stopping Coronavirus – Scientific Americcan

The goal is to identify the best means of encouraging individuals to change the way they live. Young people may need more convincing

4 Potential Treatments for SARS-CoV-2 Currently Under Testing

COVID-19 transmission messages should hinge on science – CIDRAP

What happens to people’s lungs when they get Covid-19? – Guardian

People aged 65 and over are at risk of getting pneumonia, as well as people with medical conditions such as diabetes, cancer or a chronic disease affecting the lungs, heart, kidney or liver, smokers, Indigenous Australians, and infants aged 12 months and under.

Will COVID-19 die down in summer? New tests could help answer that – Livescience

Physicists test empty coronavirus shells under different weather conditions.

Old Pancreatitis Drug May Prevent SARS-CoV-2 Infections – Precision Vaccinations

Futhan nafamostat mesylate FUT-175 blocks coronavirus from entering human cells

Vaccine Headlines

Search for Coronavirus Vaccine Becomes a Global Competition – New York Times

Any new vaccine that proves potent against the coronavirus — clinical trials are underway in the United States, China and Europe already — is sure to be in short supply as governments try to ensure that their own people are the first in line.




Chan Zuckerberg Biohub and UCSF will boost Bay Area COVID-19 tests by 1,000 per day – Tech Crunch

Oxford researchers develop new rapid test to detect SARS-CoV-2 (COVID-19) – Oxford Alumni

Published Research

Detection of SARS-CoV-2 in Different Types of Clinical Specimens – JAMA

Aerosol and Surface Stability of SARS-CoV-2 as Compared with SARS-CoV-1 – NEJM

Facing Covid-19 in Italy — Ethics, Logistics, and Therapeutics on the Epidemic’s Front Line – NEJM

Epidemiology of 2019 Novel Coronavirus Disease-19 in Gansu Province, China, 2020 – Emerging Infectious Diseases

Substantial undocumented infection facilitates the rapid dissemination of novel coronavirus (SARS-CoV2) – Science

Network-based drug repurposing for novel coronavirus 2019-nCoV/SARS-CoV-2 – Nature/Cell Discovery

Rapidly increasing cumulative incidence of coronavirus disease (COVID-19) in the European Union/European Economic Area and the United Kingdom, 1 January to 15 March 2020 – Eurosurveillance


Pre-Pub (not yet peer reviewed, should not be regarded as conclusive)

International expansion of a novel SARS-CoV-2 mutant  West China Hospital of Sichuan University-  RXiv

Molecular Dynamics Simulations Indicate the SARS-CoV-2 Mpro Is Not a Viable Target for Small-Molecule Inhibitors Design – BioRXiv

A new transmission route for the propagation of the SARS-CoV-2 coronavirus – Research Square

Infographics for Briefings

Coronavirus mapped: the latest figures as the outbreak spreads – Financial Times

Coronavirus: Everything you need to know in a visual explainer (updated daily) – South China Morning Post

Visualizing the spread of the coronavirus – USA Today

Economic Impact Infographics – Forbes

Policy & Guidance

COVID-19 Pandemic and Latin America and the Caribbean: Time for Strong Policy Actions – IMF

Economic Impact

5 Takeaways From the Coronavirus Economic Relief Package – New York Times

Senate Republicans introduced a roughly $1 trillion economic stabilization plan that includes $1,200 payments to many taxpayers, tax cuts for large corporations and limits on paid leave.

Socio-economic impacts of novel coronavirus: The policy solutions – Strides Educational Foundation



Other articles of interest